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Lopixibat chloride
CAS No. 228113-66-4
Lopixibat chloride ( LUM-001 | HP-625 )
产品货号. M13626 CAS No. 228113-66-4
Lopixibat Chloride (LUM-001, HP-625) 是一种有效的选择性口服钠胆汁酸协同转运蛋白和回肠胆汁酸转运蛋白 (IBAT) 抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥6383 | 有现货 |
|
| 10MG | ￥8748 | 有现货 |
|
| 25MG | ￥13203 | 有现货 |
|
| 50MG | ￥17658 | 有现货 |
|
| 100MG | ￥24057 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Lopixibat chloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Lopixibat Chloride (LUM-001, HP-625) 是一种有效的选择性口服钠胆汁酸协同转运蛋白和回肠胆汁酸转运蛋白 (IBAT) 抑制剂。
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产品描述Lopixibat chloride (LUM-001, HP-625) is a potent, selectiove, oral inhibitor of sodium bile acid cotransporter and Ileal bile acid transporter (IBAT).Hypercholesterolemia Phase 2 Clinical.
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体外实验——
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体内实验Maralixibat chloride reduces elevations in sBA levels, improves liver function, and reduces liver tissue damage, in a rat partial bile duct ligation model of cholestasis.
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同义词LUM-001 | HP-625
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通路Membrane Transporter/Ion Channel
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靶点ASBT Transporter
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受体ASBT Transporter
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研究领域Cardiovascular Disease
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适应症Hypercholesterolemia
化学信息
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CAS Number228113-66-4
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分子量710.415
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分子式C40H56ClN3O4S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 50 mg/mL (70.38 mM)
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SMILES——
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化学全称1-(4-((4-((4R,5R)-3,3-dibutyl-7-(dimethylamino)-4-hydroxy-1,1-dioxido-2,3,4,5-tetrahydrobenzo[b]thiepin-5-yl)phenoxy)methyl)benzyl)-1,4-diazabicyclo[2.2.2]octan-1-ium chloride
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
